When a person is annoying me specifically
He keeps interrupting me when I am busy, so he is a pain in my ass.
115👍 25👎
Someone whose sole existence is to piss you off and bother you.
John, you are being a really big pain in my ass today.
29👍 9👎
a: youre such a pain in my ass
7👍 3👎
a real pain after a person experienced anal intercourse
Ouch, I need to go to the doctor because I have pain in my ass.
44👍 43👎