A pincushion is a person who is addicted to heroin, they have been jabbed with countless needles therefore pincushion medicine is the heroin itself.
Layne Staley, the heroin addicted lead singer for Alice in Chains wrote in his song 'Hate to Feel' -
"gotta get
Pincushion medicine
Used to be curious
Now the shit's sustenance", referring to heroin.
:)
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