An insult used to wish someone to quite literally, piss out blood, as if they have a symptom or illness which causes them to.
Similar to 'get cancer' or 'die'
A: Why are you always alone, nerd?
B: Go piss blood.
Lucifarians, all an any of them.
Oh look, John joined a silly cult of the piss blooded, what a fool, bet he stinks from the inside out haha.
Someone who gets cold easy, doesn’t like the cold
Charlie: Man I’m freezing.
John: What’s wrong with ya? Got piss in your blood?