The act of inserting a tampon at that time of the month.
Annie said, "I need to stop at CVS so I can plug my bug!"
Someone who has fallen off the face of the Earth after being super famous and/or popular
or
Someone who has gone from hetero-God to dead by sexually transmitted disease very suddenly and without much fanfare
Hey what happened to Sisqo anyways? I heard he got plugged and bugged and checked out years ago...
No, man...he didn't Eazy-E it or nothing, he was on Celebrity Big Brother in the U.K.