1. Phrase uses to indicate one would be willing to have sexual intercourse with a female.
2. Phrase used to imply sarcasm towards a female. Another way to say big deal.
1. What you think about that girl over there? Pootie do or pootie don't?
2. She's walking around bragging about working out for, a grand total of, one day. Pootie do!! Real lifestyle makeover.