Blindsiding an unsuspecting douchebag or idiot with your fist after building momentum and launching from a full sprint.
Look at that loser wearing the VR headset. I just want to run punch that stupid smile off his face. He'll never see it coming!
When your playing JoJo Blox and you punch a thug and run away.
Yo Tony, i totally Punch-runned a thug yesterday.