to have RG Syndrome you must be unable to receive an erection. One who suffers from erectile dysfunction.
teen 1: I heard Tom Cruise has RG Syndrome. Do you know of any truth is this?
teen 2: I don't know, you'd have to ask his wife.
It stands for Ruru-Genshin syndrome. Someone's computer/laptop/mobile is said to have RG-syndrome when their device lags/crashes excessively due to low RAM/ crappy graphic card/ shitty wifi- usually happens while playing Genshin Impact but might occur during other times too.
Person 1: Man, my laptop's been laggin like shit. Ion know what's happening.
Person 2: LMFAOO L bozo. You've got RG-syndrome duh.