Sister with a blister

1. Referring to a female that is known to have a sexually transmitted (venereal) disease.

Dude, I'm going to ask Dolores out next Saturday.

Don't do it man! She is the Sister with a blister!

Man, she is so HOT! Can't belive she is the sister with a blister.

sister blister

I sister/friend that is hot like a burn/blister on the inside and on the outside

Nah bruh, I can’t date her.. she’s my sister blister!