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A way to say "that's gross" or "screws" or "just gross" interchangeably. Can also be spelled scrus, skrus, sckrus, scroose or sckroose.
Eric: "What are you gonna do with all these skroose?"
Sara: "I'll tell you what I'm not gonna do, you!! Because that's skroose!"
-Or-
Fuzz: "Hey, did you meet that one puke at the party last night?"
Teek: "Yeah he was all over me, skroose!"