A reference to the fact that semen is not a pure white color, but an off white color. A person who doesn't smoke would have pure white teeth, but a smoker's teeth would be off white.
Also coined as a gaming term, used when you have defeated your opponent; referencing that you have defiled your opponent by busting a load of man gravy on their face.
I busted smoker's teeth on that dude's face when I got a headshot on him in Resistance: Fall of Man.
You are about to get some smoker's teeth after I own you at Modern Warfare 2.