Supayeso?

A quick, nice, and lazy way of calling your boy an Asshole while asking him "What's up?"

What's up, Asshole?
Hey, so what's up, Asshole?
Aye, so what's up?
Ayeso, what's up? (sentence structure inverts into...)
What's up, Ayeso?
'sup, Ayeso?
Supayeso?

"Supayeso?"
"Not much, Ayeso"

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