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When your balls are sweaty such as excersize such as fuckin' a girl, playing in the marching band, or doing jumping jacks in 100 degree weather
After Johnson blew his flute and marched around he contracted a case of sweaty ball syndrome
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Sweaty ball syndrome or SBS is what happens when you get done with a workout and your balls are just dripping sweat, it also happens when you play sports or sleep.
Me: Dude! After that workout I have some severe Sweaty ball syndrome!
Friend: You mean SBS?
Hey babe, after sleeping last night I have some major SBS.