An even more hyperbolic variant of The 50-50-90 Rule. In a situation where a subject has a 50/50 percent chance of getting something right, they will get it wrong 100% of the time.
This "rule" was popularized within the Super Mario Maker troll level community by popular Twitch streamer CarlSagan42, and is just one example of a reoccurring joke designed to showcase how easy it is to fool the average player into doing something wrong.
Player: *decides to collect a powerup which the level kills them for in the next room* "It's LITERALLY The 50-50-100 Rule. This happens EVERY time!"