When a song has an awesome build up to the drop and then ruins it all when the drop actually happens.
*listening to music that's about to hit the drop*
Guy1: "Holy shit this song is freaking amazing!"
Guy2: "I cannot wait to see what happens after the drop."
*Song ruins itself with shitty music after the drop*
Guy1: "Dafuq is this?"
Guy2: "This song has The Drop Syndrome. :( "
A medical condition mostly prominent in the elderly community in which a large flatulence is expelled so violently the victim loses their footing and fall over as a side effect.
They lady who fell over at the line in Luby's to first responders that she has Hindermen's Drop Syndrome as a pre-existing condition.
The negative sensation one encounters upon discovering their Facebook friend numbers dropping.
Another one? Friend Drop Syndrome.
When the second drop in a dubstep/trap song doesn't come anywhere close to the first
Man, that new skrillex song has an awful case of second drop syndrome.