The act of aggressively jerking another person off with a prosthetic hand that is lathered up with guacamole, sour cream, and beef chili.
Joanne: How was your date at that Mexican restaurant last night?
Sally: Quite delightful. I gave Frank The Guatemalan Handshake under the table before our entrees came.
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The act of removing a dirty sanchez.
After her dirty sanchez, Liesa retired to the bathroom for a Guatemalan handshake.
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A handjob in which Latin American/Mexican dressings/condiments are used as lube. I.E. salsa, guacamole, sour cream, hot sauce (if you're kinky) etc.
I was with this totally hot puerto rican chick last night.
Dude, did you bang her!?!
Nah, but she did give me a Guatemalan handshake.
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