When someone (particulary a female) starts acting like a toxic bitch and they usually have the syndrome from birth, but the symptoms typically surface in their prebescent stage of their lives and progress from there. There is no known cure, but there are several treatments to avoid and prevent flare ups. You can live with someone with the syndrome, but if left untreated it can lead to complete loneliness, unemployment, isolation, alienation, and down right despisement by the direct communities they effect in extreme cases.
Kyla was diagnosed with toxic bitch syndrome by her psychiatrist when she turned 16, so the doctor prescribed her 1000 mG of prozac to control the mood flare ups at school.