flipping the fuck out on cocaine, meth, caffine, nicotine, ect.
"Dude did you see Sarah last night she was all twigged out doing cartwheels and shit!"
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A term to describe a hella skinny person.
Dude, that chick is hella twigged out! That's nasty!
Lyndsay Lohan is mad twigged out!
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A term referring to a state of mind. Meaning out of it, feeling separated from society and your normal life. Possibly a loss of your self identity. Usually used in context with LSD.
After that crazy acid trip, Sid was really twigged out.
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