A Brazilian slang for "anal sex". It is used to offend someone and/or express anger. It's equivalalent in English would be "Go take it in the ass!".
*Two buddies Super Smash Bros*
BUD1: *Chooses Pikachu and reapeatedly uses Thunder Shock*
BUD2: Ah, qualé mano Vai dar o cu!
(Oh, c'mon dude! Take it in the ass!)
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