It means exactly what it seems. A simple and common proverbial phrase, arguing what goes up must come down.
The example below is an except from 'Human Traffic' (1998), an independent British film said by character Jib.
What goes up must come down, and down, and down. Everyone looks ill at the end of the night. All have lost the power of speech, desperately avoiding eye contact. Your new soulmate, that you have been talking cod shit to for the past five hours about the story of creation or the fourth Star Wars film, is now a complete stranger.
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