It is the effect applied to someone who becomes a go-to person for people who are not happy with their relationship or generally depressed. Often the vent of someones emotions.
It's also used sarcastically for people who think highly of themselves.
Person A: "Man, people go to me everytime they need advice about their partners or when they're feeling down. I get a boost of serotonin when they listen to me."
Person B: "Sounds like you got the Zi Effect on you."