To become aroused, making hawt secretions come out of your vagina.
It happens when you see something sexualy stimulating, such as a guy with awesome hair or V lines.
Figure.10: "Ok, now we're going to watch Harry Potter and The Goblet of Fire-"
*fangirl scream*
Figure.10: "Please people, try not to cream your panties."
*all fail*
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when a female sees an attractive guy and gets a sudden arousal in the genital area.
"omg that guy just made me cream my panties"
"that boy is so fine i just creamed my panties"
"ohh girl i just creamed my panties"
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A females panties that are put on after sex or in some cases penetration occurred while wearing the panties and the load of cum oozes through the front of the panty area making them appear very wet and moist.
After Dave shot his load in his girlfriend, the oozing fluid of white liquid was the cream of panties.