despair disease

Despair Disease is a motive introduced in the third chapter of Danganronpa 2: Goodbye Despair. It's an endemic disease that is found on Jabberwock Island. According to Monokuma, there are extremely tiny insects that transmit the disease.In truth, it's a fictional disease that exists only in the Neo World Program's virtual version of the island. "The insects" appear to be just a story made up by Monokuma, who can cure and supposedly inflict the disease in a flash.

“Oh no, I have a disease! walking around in your Neighborhood, spreading all my flees. Everybody like ‘what you got?’ And I’m like.... despair disease!”