To screw up really bad.
To not show up at all and the people waiting for you are screwed because you flaked out.
Damn it! Our drummer is not going to make it tonight. Looks like he dicked the show again.
I dicked the show and forgot to pick up beer. Shit! You have any money?
We are going to run out of gas! Dude, you totally dicked the show. Why didn't you get gas?