Expression used in spiritual/philosophical circles referring to an unmediated experience of transcendence or the numinous, usually achieved through meditative/introspective practices - such as 'self-inquiry' - or through the use of psychedelics. Synonymous with the mystical experience.
Ramana Maharshi underwent direct experience as a 14-year old.
I had a direct experience by doing 5 grams of dried psilocybin mushrooms.