The smoke that is left in the chamber of a bong when a smoker cannot pull all the smoke through in one hit.
Carson: yo tom, i cant finish this bong, take it.
Tom: screw that man, i aint taking that dirty chamber.
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When you go out sober and hit on every girl (and or boy) in hopes of getting your dick wet.
Last night I went to Jay's and pulled a Dirty Chambers