To completely rid yourself of the nuisance of someone else's presence. This often involves beating the proverbial, living sh*t out of said nuisance, or putting their corpse six feet under--whichever is preferred in order to achieve the desired result. You may substitute names, proper nouns of gender, and mix names, proper nouns, and expletives to ensure the proper result of your speech.
He spilled all my liquor! I'm about to dust him off!
Mr. Officer, he ran the red light and hit my brand new truck! He's lucky I didn't dust his ass off!
If I hear that this trick is trying to keep me away from my kids, I'm gonna have to dust her off!
Don't be mad because she chose me! You know the rules! Keep acting up, and I'm gonna dust yo' ass off!
Bro, I'm surprised you let Jenna get away with stealing all your money. If I were you, I would've dusted that bitch off!
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