Can refer to either:
(1) Conditions so frustrating/stressful/frightening that you cannot help shrieking in terror or exasperation, or
(2) A situation where you are obliged (or feel free!) to holler at your former lover/spouse.
Against my better judgement, I took a middle-aged alcoholic dude to see his former girlfriend about the possibility of his moving back in with her. She was visibly annoyed at the encounter and even seemed somewhat put out with **me** for even having brought that deadbeat to her house in the first place, so I treaded super-lightly, gently explaining to her that the guy had merely asked me for a ride there ("I know nothing about this matter, Ma'am; I'm just the driver."); I could clearly see that these were definitely exscream circumstances.