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Slang meaning "full of energy."
She's like the Energizer Bunny, always full of piss and vinegar.
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being a puppy who is extremely excited and rowdy, often causing a wake of destruction in their path.
my puppy is full of piss and vinegar today. She messed on the floor, chewed the tp, a kleenex box, my fav pair of shoes and my book!
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