getting on my nerves

When someone's being annoying and you're wishing they'd stop.

While travelling:
son: "are we there yet?"
father: "no"
son: "are we there yet?"
father: "you're getting on my nerves"

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get on my last nerve

Means when you are ready to lose your temper

You are about to get on my last nerve if you keep asking stupid questions.

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