Usually applies to a person, but can be a place or thing. Implies such noun is classified as a regular or permanent characteristic/ trait of the hood.
"You're so ghetto - reg ; you're never going to leave the hood!"
Or, "I should have known not to shop at the swap meet. The inside of that place has 'ghetto-reg' written all over it!"
And, "Could his pants fall any further from his behind? That is so ghetto-reg."