gone in the head

A person who is considered to be crazy; who does things which aren't generally accepted or which are out-of-character.

That guy is gone in the head, you can't do things like that here.

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You Should Have Gone For The Head

Fat Thor holding a hammer and an axe trying to kill papa Thanos with a rock collection and forgot about bringing Ant Man to fight Thanos.

Also found in Death Note where Saitama got sniped by Goku just because he forgot to go for the Ant Man on Goku's head.

Thanos:"You Should Have Gone For The Head."