cold and/or cough syrup, especially NyQuil. such OTC medications cause drowsiness, so a mild overdose will cause unconsciousness. utilised especially by exasperated caretakers (e.g. parents and babysitters) and insomniacs without access to sleeping pills.
Jenny the babysitter couldn't get little Billy to shut the fuck up, so she gave him some goodnight juice and tucked him in to bed.
It was four in the morning, and Jacob had to get up at six. He took some goodnight juice, and was asleep within minutes.
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