hoobie jube

Marijuana; cannabis sativa
also
the substance, that, when smoked, makes Orion go crazy

Orion: "I need a bottle of Sweet Vermouth! Yes! The whole thing! It's the demon, you know!"
Others: "Oh shit, Orion's gotten into the hoobie jube; he told us not to let him get into the hoobie jube because it makes him go crazy.