When you fart immediately after getting out of the shower, thereby negating its effects.
"Aww, man!" "What?" "I just got out of the shower, and i think that fart was wet... Instant Regret"
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Inviting Big E to your bachelor party and realizing he is going to bring up memories of it for the next 48 years
Hey Sarah I heard you hooked up with some random kid at a party last night?
Yeah, talk about instant regret