Issa vibe basically is saying "it's a feeling"
Raining or dark out side- issa vibe
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Issa being the short slang term for "It's" and vibe meaning feeling or someones emotional state, putting them together should ultimately create something its a feeling.
Will: Hey, I heard you asked out Dana yesterday? What's going on?
Richard: I don't know man, issa vibe.
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