Shot with a gun, usually in an especially violent or agressive manner. This word derives from southern street gangs, and is likely a mixture of "kablammed" and "funked."
"I hear he got kafunked last night in the alley way by those Bloods."
When your physically and emotionally depleted and you don't have capacity to give any more.
We've just had my sisters 5 kids staying with us for the last week. It was great but I am totally kafunked.