A descriptive measure of a woman's predisposition to engage in sexual activities.
AKA: Down to Fuck, Puts Out, Down with the D
Person A: Hey, you that chick over there?
Person B: Yeah, I bet she knows whats up.
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If one knows what's up - they got it, have it figured out, the one you can trust in the specific situation they're the one to follow.
*someone talking about politics and solidarity on the telly* yeah, he knows what's up!
To know everything about something
Boady is sure knowed up on collecting purple shit
What you tell them you said instead of "blow up"
This whole room is rigged to blow up!
"BLOW UP!? I'm outta here!"
No, I said know up!