To go mad, crazy, stop thinking right, or to lose your mind
“Mum said I lost the plot, at least I never lost my crop”
Acting out of character.
Behaving abnormal, weird or crazy.
She just sits there, staring at the walls. I think she has lost the plot
Dad completely lost the plot when he saw my picture on the front of the porno DVD.
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When you’re doing the ultimate nasty and the receiving partner enters a blissful state of confusion
“Last night I was giving it to Priscilla so hard she lost the plot, couldn’t even remember her name.
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Slang for when someone loses there focus or ends up failing to do what the had set out to do.
When I failed my chemistry test, I had lost the plot.
I was telling my friend a funny story, but then I lost the plot and started talking about my grandmother’s brownie recipe.