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The worst type of bitch, one who is a "mark", which means that he/she is a target that is very vulnerable to attack from others. Like a sitting duck. Calling someone this implies that you intend to murder them or do them harm in some way, or that you suspect someone else will, and that they deserve what's coming to them.
"Biggie Smalls and Jr. Mafia some mark-ass bitches." -2pac ("Hit 'em up")
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Suspect; Someone who is marked for death; A target.
"Biggie Smalls and Junior MAFIA are some Marked Ass Bitches!" - 2Pac
"That nigga is playing us like a couple of Marked Ass Bitches!" - Larry Bacchus
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Dumb bitch that always wants shit...money, going out places...but is a tease at the same time... therefor making her a trick and a mark ass at the same time. money sucking bitches/tricks.
hoe-hey you going out tonite?
guy-hell naw you mark ass bitches dont give me shit in the bedroom, and worst yet you dont even pay me back with yo broke ass.
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Something you might call someone in a moment of extreme anger, and are probably about to blast on them! Its also what the GTA: San Andreas character "OG Loc" calls Lazlow during a radio interview.
You down? You mark-ass bitch, punk, trick, busta, fool!!
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