The act of murder. Playing the murder game is something a murderer does.
"i layed the murder game down lettin' those niggas know we ain't fuckin around B" ~Paid In Full
To participate in the act of killing ones rivals, former friends, or any punk muthafucka who who talks shit, or double crosses them.
Yo that nigga Calvin was talking shit so i had to lay down the murder game down real quick and that nigga is invisible now.