The place where illegal drugs are made, sold, and used. (see also, unemployment office)
"Hey, Fred, wer'e goin' to the nigger's den to smoke some grass!"
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Alternatively spelt niggerden or nigger den.
A broken down suburban house (usually in cities like Detroit, Chicago or Jackson) that has paint coming off and has obscene things spray painted all over it and generally looks abandoned. If not likely to be used by a gang it sure looks like it, might just be the place that some innocent blacks who happened to be born poor into a shithole have to live.
"Look at this Chicago style gingerbread house someone made"
"This looks like a nigger-den"