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Th definition of taking a giant shit in your toilet, so it feels like it should eksplode.
I need to go use the bathroom, so i can nuke the toilet
Like dropping a nuke only much worse, most of the time bad enough to back up your sewage system.
Man I had to call the plumber after I nuked the toilet in my house last night.
Taking a dump and seeing that you broke it
Person: dude you nuked that toilet!
(Ignore this nuking a toilet
a toilet that was nuked by someone's shit
"Thats a Nuked toilet in Taco bell. Im not suprised."