When you are trying to hook up with a girl and she isn't showing any interest so, you move on to the next one.
BRO(1): Bro, this girl taking this bate?!
BRO(2): Don't even trip Bro, on to the next one!
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To move on to the next available, hot female whether in person or on video chat. On To The Next One (OTTN1) was a saying used originally by Charles Kast and Corey Rother, as they mac'd on chicks.
Britany_bunny69 : Omg my cam just broke sorry guys, holdon while I try to figure out whats wrong with it.
Gino : Man... WTF? OTTN1
Anthony : Wtf is OTTN1??
Mc : It's On to the next one fool!
Josh : I'm hungry
KPS
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when you're no longer stimulated/intrigued/pleased/interested/aroused and move on to the next one
Dexter was getting boring so I moved on to the next one
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We shall present our proposals the next week but one
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you know you're going to be next person to be successful in (anything); a feeling of greatness/determination/certainty
Person 1: Hey, you're really good at this.
Person 2: yeah, I'm the next one up