When a lesbian experiences strong and uncontrollable urges for penis.
Gretchen: "I've got penis fever."
Carol: "But we're lesbians!"
Gretchen: "I know. But years ago I had a taste of the penis, and despite now preferring the puss I just really want some penis."
Carol: "But why?"
Gretchen: "Because fists don't ejaculate."
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When a girl has sex with a guy, and then is hooked on that guy for a real long time
The Main bri: I just had sex with this girl and she doesn't want to leave me alone.
The nigs friend: Bruh she has Penis Fever