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Penis-at-12 syndrome

A 5-alpha reductase deficiency at birth causes ambiguous to female-type external genitalia. The male has undescended testes. The deficiency essentially prevents testosterone from becoming dihydrotestosterone (DHT). Now the penis-at-12 syndrom itself occurs around puberty when the high levels of testosterone overcome the requirement of DHT...the clitoris enlarges, alas, "penis-at-12".

Damn, I'm sure glad I don't have penis-at-12 syndrome.

by eleven April 28, 2003

94👍 21👎