Perpetual bitch syndrome is when a male loses all of his masculine characteristics due to severely low testosterone levels. Someone suffering from perpetual bitch syndrome will undoubtedly cruise through life as spineless, weak-willed loser who only can find a small and dim lit happiness either in the bottom of a bottle or from their ugly slag partner that is barely an excuse for a woman.
Man 1: “Dam Tony acts a different after he got his new girlfriend” Man 2: “Its pretty sad, he's unfortunately suffering from perpetual bitch syndrome.”