When someone is so damn fucking annoying, you could fire several shots through you skull and live just to feel the pain as it'd be better than whatever the person is doing, whilst the lead is still lodged in your temple you wish upon a migraine from the holy gods just to comfort the sheer annoying pain of whatever the person is doing.
"Oh my, Brenda was so piss annoying yesterday I wanted to literally kill myself!"
When you're so annoyed that you could piss yourself.
Serena got me pissing annoying!