Similar to frape, a profile screw is when you either:
1. know somebody's facebook password and log into their account from home, to then frape them
or
2. someone has left themselves logged onto facebook on your computer/phone and you then frape them later on
Dude, wtf, my status just changed to 'I am gay'
ahh yeah, Dom told me he had your password, guessing he's profile screwing from home