regulate your genitals

Another way of saying "Calm your tits!"

Richard: Oh my god, Jeffrey is totally hitting on me, ugh.
Fabrizio: In your dreams fam, he's definitely gawking at that absolute Chad behind you.
Richard: Do you not see him, he totally wants to get it on. Look at him, drooling!
Fabrizio: Dude, ya gotta regulate your genitals ma man. Maybe lay off the booze for now.