any female of above average height,and size
"dude did you see the new security guard she is 3 feet taller than you and can palm a basketball",,,,"yeah she is a shesquatch"
A really hairy bitch badly in need some lady-scaping.
Damn, you see the hairy arms on that shesquatch you went out with last night?
Large smelly Alabama woman with a pussy the size of a truck that smells like maggot butt sex. May also be referred to as a Yeti-Cunt-A-Sarus
That bithch so fucking nasty. She's a Shesquatch.